Liverpool will go up against German mammoths Bayern Munich in the Champions League last 16, while Manchester United have been drawn against Paris St-Germain.
Head League champions Manchester City and Tottenham additionally confront Bundesliga sides, with City meeting Schalke and Spurs playing Borussia Dortmund.
The main legs will happen on 12-13 and 19-20 February, with the arrival installations on 5-6 and 12-13 March.
Gathering victors will be far from home in the main legs.
Groups couldn’t be drawn against sides from a similar nation in the last 16, nor against groups who they played in the gathering stage.
Somewhere else, holders Real Madrid will confront Dutch victors Ajax, who have achieved the knockout stages out of the blue since 2005-06, while Serie A heroes Juventus confront Europa League champs Atletico Madrid.
Spanish victors Barcelona meet French side Lyon, while Italian club Roma confront Portuguese bosses Porto.
Come back to Germany for Klopp
Liverpool, who lost 3-1 to Real Madrid in last season’s conclusive, maintained a strategic distance from a rematch with the Spanish goliaths in Monday’s draw when they were left in the pot of unseeded groups with Ajax – who played Bayern in the gathering stage.
Ex-Reds winger Steve McManaman trusts his previous club have the quality to beat Bayern.
“Liverpool were continually going to get a troublesome draw,” the previous England universal said on BT Sport.
“No lack of regard to Porto, yet they are presumably the one group you needed to draw.
“Be that as it may, Bayern Munich are the not the group they used to be. This youthful, rich, fast Liverpool group ought to be unreasonably bravo.
“This squad is faster, more grounded and better for the experience after a year ago.”